Zhong Group
Publications prior to NTU
30. Darmon, J. M.; Zhang, T.; Zhong, H.; Ho, S.; Cao, G.; Chirik, P. J. Flash Communication: Carbon Monoxide Insertion and Ligand Modification with Pyridine(Diimine) Iron Alkyl Complexes. Organometallics 2024 [Link]
Sci. Bull. 2024, 69 (3), 290–292. (Research Highlight) [Link]
28. Cai, S.; Yu, R.; Li, C.; Zhong, H.; Dong, X.; Morandi, B.; Ye, J.; Fang, X. Nickel-Catalyzed Enantioselective Hydrothiocarbonylation of Cyclopropenes. Org. Lett. 2023, 25 (48), 8683–8687. [Link]
27. Zhong, H.; Egger, D. T.; Gasser, V. C. M.; Finkelstein, P.; Keim, L.; Seidel, M. Z.; Trapp, N.; Morandi, B. Skeletal Metalation of Lactams through a Carbonyl-to-Nickel-Exchange Logic. Nat. Commun. 2023, 14 (1), 5273. [Link]
Highlighted by Communications Chemistry. Nature News Feature.
26. Park, Y.; Zhong, H.; P. Pabst, T.; Kim, J.; J. Chirik, P. Pentamethylcyclopentadienyl Metalloradical Iron Complexes Containing Redox Noninnocent α-Diimine-Type Ligands: Synthesis, Molecular, and Electronic Structures. Organometallics 2023, 42 (6), 465–472. [Link]
25. Lutz, M. D. R.; Zhong, H.; Trapp, N.; Morandi, B. Synthesis and Reversible H2 Activation by Coordinatively Unsaturated Rhodium NHC Complexes. Helv. Chim. Acta 2023, 106 (4), 1–9. [Link]
24. Kim, S.; Kim, J.; Zhong, H.; Panetti, G. B.; Chirik, P. J. Catalytic N–H Bond Formation Promoted by a Ruthenium Hydride Complex Bearing a Redox-Active Pyrimidine-Imine Ligand. J. Am. Chem. Soc. 2022, 144 (45), 20661–20671. [Link]
23. Mendelsohn, L. N.; Pavlovic, L.; Zhong, H.; Friedfeld, M. R.; Shevlin, M.; Hopmann, K. H.; Chirik, P. J. Mechanistic Investigations of the Asymmetric Hydrogenation of Enamides with Neutral Bis(Phosphine) Cobalt Precatalysts. J. Am. Chem. Soc. 2022, 144 (34), 15764–15778. [Link]
22. Pavlovic, L.; Mendelsohn, L. N.; Zhong, H.; Chirik, P. J.; Hopmann, K. H. Cobalt-Catalyzed Asymmetric Hydrogenation of Enamides: Insights into Mechanisms and Solvent Effects. Organometallics 2022, 41 (14), 1872–1882. [Link]
21. Zhong, H.; Morandi, B. Carbon–Carbon Bond Formation in Reverse. Nat. Synth. 2022, 1 (4), 264–266. (News & Views) [Link]
20. MacNeil, C. S.; Zhong, H.; Pabst, T. P.; Shevlin, M.; Chirik, P. J. Cationic Bis(Phosphine) Cobalt(I) Arene Complexes as Precatalysts for the Asymmetric Synthesis of Sitagliptin. ACS Catal. 2022, 12 (8), 4680–4687. [Link]
19. Beromi, M. M.; Younker, J. M.; Zhong, H.; Pabst, T. P.; Chirik, P. J. Catalyst Design Principles Enabling Intermolecular Alkene-Diene [2+2] Cycloaddition and Depolymerization Reactions. J. Am. Chem. Soc. 2021, 143 (42), 17793–17805. [Link]
18. Park, Y.; Kim, S.; Tian, L.; Zhong, H.; Scholes, G. D.; Chirik, P. J. Visible Light Enables Catalytic Formation of Weak Chemical Bonds with Molecular Hydrogen. Nat. Chem. 2021, 13 (10), 969–976. [Link]
17. Park, Y.; Semproni, S. P.; Zhong, H.; Chirik, P. J. Synthesis, Electronic Structure, and Reactivity of a Planar Four-Coordinate, Cobalt–Imido Complex. Angew. Chem. Int. Ed. 2021, 60 (26), 14376–14380. [Link]
16. Rummelt, S. M.; Peterson, P. O.; Zhong, H.; Chirik, P. J. Oxidative Addition of Aryl and Alkyl Halides to a Reduced Iron Pincer Complex. J. Am. Chem. Soc. 2021, 143 (15), 5928–5936. [Link]
15. Zhong, H.; Beromi, M. M.; Chirik, P. J. Ligand Substitution and Electronic Structure Studies of Bis(Phosphine)Cobalt Cyclooctadiene Precatalysts for Alkene Hydrogenation. Can. J. Chem. 2021, 99 (2), 193–201. [Link]
14. Kim, S.; Zhong, H.; Park, Y.; Loose, F.; Chirik, P. J. Catalytic Hydrogenation of a Manganese(V) Nitride to Ammonia. J. Am. Chem. Soc. 2020, 142 (20), 9518–9524. [Link]
13. MacNeil, C. S.; Mendelsohn, L. N.; Zhong, H.; Pabst, T. P.; Chirik, P. J. Synthesis and Reactivity of Organometallic Intermediates Relevant to Cobalt-Catalyzed Hydroformylation. Angew. Chem. Int. Ed. 2020, 59 (23), 8912–8916. [Link]
12. Zhong, H.; Shevlin, M.; Chirik, P. J. Cobalt-Catalyzed Asymmetric Hydrogenation of α,β-Unsaturated Carboxylic Acids by Homolytic H2 Cleavage. J. Am. Chem. Soc. 2020, 142 (11), 5272–5281. [Link]
11. Peterson, P. O.; Rummelt, S. M.; Wile, B. M.; Stieber, S. C. E.; Zhong, H.; Chirik, P. J. Direct Observation of Transmetalation from a Neutral Boronate Ester to a Pyridine(Diimine) Iron Alkoxide. Organometallics 2020, 39 (1), 201–205. [Link]
10. Kennedy, C. R.; Zhong, H.; Joannou, M. V.; Chirik, P. J. Pyridine(Diimine) Iron Diene Complexes Relevant to Catalytic [2+2]-Cycloaddition Reactions. Adv. Synth. Catal. 2020, 362 (2), 404–416. [Link]
9. Kennedy, C. R.; Zhong, H.; Macaulay, R. L.; Chirik, P. J. Regio- and Diastereoselective Iron-Catalyzed [4+4]-Cycloaddition of 1,3-Dienes. J. Am. Chem. Soc. 2019, 141 (21), 8557–8573. [Link]
8. Zhong, H.; Friedfeld, M. R.; Chirik, P. J. Syntheses and Catalytic Hydrogenation Performance of Cationic Bis(Phosphine) Cobalt(I) Diene and Arene Compounds. Angew. Chem. Int. Ed. 2019, 58 (27), 9194–9198. (VIP) [Link]
7. Rummelt, S. M.; Zhong, H.; Léonard, N. G.; Semproni, S. P.; Chirik, P. J. Oxidative Addition of Dihydrogen, Boron Compounds, and Aryl Halides to a Cobalt(I) Cation Supported by a Strong-Field Pincer Ligand. Organometallics 2019, 38 (5), 1081–1090. [Link]
6. Zhong, H.; Friedfeld, M. R.; Camacho-Bunquin, J.; Sohn, H.; Yang, C.; Delferro, M.; Chirik, P. J. Exploring the Alcohol Stability of Bis(Phosphine) Cobalt Dialkyl Precatalysts in Asymmetric Alkene Hydrogenation. Organometallics 2019, 38 (1), 149–156. [Link]
5. Rummelt, S. M.; Zhong, H.; Korobkov, I.; Chirik, P. J. Iron-Mediated Coupling of Carbon Dioxide and Ethylene: Macrocyclic Metallalactones Enable Access to Various Carboxylates. J. Am. Chem. Soc. 2018, 140 (37), 11589–11593. [Link]
4. Friedfeld, M. R.; Zhong, H.; Ruck, R. T.; Shevlin, M.; Chirik, P. J. Cobalt-Catalyzed Asymmetric Hydrogenation of Enamides Enabled by Single-Electron Reduction. Science 2018, 360 (6391), 888–893. [Link]
3. Morello, G. R.; Zhong, H.; Chirik, P. J.; Hopmann, K. H. Cobalt-Catalysed Alkene Hydrogenation: A Metallacycle Can Explain the Hydroxyl Activating Effect and the Diastereoselectivity. Chem. Sci. 2018, 9 (22), 4977–4982. [Link]
2. Obligacion, J. V.; Zhong, H.; Chirik, P. J. Insights into Activation of Cobalt Pre-Catalysts for C(Sp2)−H Functionalization. Isr. J. Chem. 2017, 57 (10), 1032–1036. [Link]
1. Bender, T. A.; Dabrowski, J. A.; Zhong, H.; Gagné, M. R. Diastereoselective B(C6F5)3-Catalyzed Reductive Carbocyclization of Unsaturated Carbohydrates. Org. Lett. 2016, 18 (16), 4120–4123. [Link]